A quartz crystal microbalance biosensor based use of pesticide as recognition bed for detection of HSA

Abstract

A quartz crystal microbalance biosensor on the interaction of thiophanate methyl (MT) with human serum albumin (HSA) has been prepared. The human serum albumin was immobilized onto surface of Au coated MT as a biosensor for the detection of HSA protein by quartz crystal. Kinetic parameters of the HSA and MT interactions were also determined. The first-order rate constant k value was found to be 0.047 min-1. The frequency–time profile suggests that the adsorption of HSA is controlled by activation kinetic. The obtained results indicate that HSA can provide a promising material for the biosensor designs and other biological applications.