Production and Characterization of Nanotechnological Tape for Wounds Caused by Diabetes

Abstract

It is aimed to produce wound dressing from natural resources with electrospinning, which is a nanotechnological method for the rapid healing of wounds of diabetic patients. In this study, polyvinyl alcohol (PVA), which is very useful for electrospinning method in terms of its properties such as being easily soluble in water, easy spinning, and forming qualified nanofiber surfaces, was used. A mixture of 10% by mass of PVA in granular form and pure water was prepared by weighing on a precision scale. The mixture was stirred on a heated magnetic stirrer at 80 ^oC for 3 hours and left at room temperature for 24 hours. 5% St. John's Wort (H. perforatum l.) (S.J.W.) and Calendula  (Calendula officinalis) (A.) additives were added to the 10% PVA solution formed and mixed in a magnetic stirrer at 30 ^oC for 45 minutes. 10% PVA, 10% PVA-5% S.J.W., 10% PVA-5% A. and 10% PVA-5% A.-S.J.W. composites were obtained by electrospinning technique. The body needs calories, protein, vitamin A-C and zinc to heal wounds. 10% PVA, 10% PVA-5% S.J.W., 10% PVA-5% A. and 10% PVA-5% A.-S.J.W. without causing possible allergic reactions composites have been successfully obtained.